Longevity

The Einstein Institute for Geroscience, formerly the Institute for Aging Research, studies the biological pillars of aging to develop thera…

The FLI in Jena is a German Leibniz institute dedicated to basic research on the biology of aging and age-related disease.

Research and public-interest longevity media

The Longevity Consortium is an NIA-supported research network studying exceptional human longevity that offers Translational Opportunity Fu…

The LEV Foundation runs combination-intervention rejuvenation studies in mice aimed at extending healthy lifespan.

Biology of aging research

The NIA-funded Nathan Shock Centers are eight research centers that provide cores, pilot awards and resources for basic biology of aging re…

The Harvard Glenn Center groups laboratories studying the genetics and epigenetics of aging with the goal of interventions that extend heal…

The Kogod Center on Aging at Mayo Clinic conducts research on the biology of aging, including cellular senescence, and translates it into c…

The Barshop Institute at UT Health San Antonio runs research centers, cores and clinical trials on the biology of aging and age-related dis…

The UCL Institute of Healthy Ageing is a research center on the biology of aging and aging-related disease using yeast, worms, flies and sh…

The University of Copenhagen Center for Healthy Aging was an interdisciplinary center on the biology and health of aging.

The Geneva College of Longevity Science offers an executive master's and a PhD specialization focused on longevity medicine and the biology…

A Stanford research center examining how technology, policy, and behavior can improve longer lives.

Extending healthy human lifespan through research and innovation.

Immortal Dragons is a Singapore-based $40 million longevity fund investing in pre-seed to Series A life extension startups and in other lon…

Investing in rejuvenation biotech for healthier lifespans.

Investing in the future of biotechnology and longevity.

Advancing human longevity through innovative research funding.

Investing in the future of longevity.

Extending healthy human lifespan through biotechnology.

The Methuselah Fund is a venture fund affiliated with the Methuselah Foundation that invests in companies extending healthy human lifespan…

Norn Group is a longevity do tank that runs Impetus Grants, talent programs and field roadmapping to speed aging research into medicines.

Investing in revolutionary technology for a better future.

U.S. health research agency funding ambitious programs, including organ-chip work in space.

Investing in the future of longevity and mental health.

The Hillblom Foundation funds California research on diseases of aging, mainly brain and vision, and has made 185 aging-related grants.

Investing in the future of longevity.

The Longevity Company Builder

Investing in the future of neuroAI and longevity.

Investing in the future of longevity biotechnology.

Wellcome Leap runs the $60M Dynamic Resilience program to find biomarkers and mechanisms of resilience and frailty in aging.

Incentive competitions for breakthroughs

clock.bio maps genes that regulate cellular aging and measures cell age with machine learning to develop rejuvenation interventions, starti…

Cyclarity Therapeutics, a SENS Research Foundation spinout formerly called Underdog Pharmaceuticals, develops a cyclodextrin that removes 7…

Deciduous Therapeutics develops immunotherapies that restore the immune system's ability to clear senescent cells that drive age-related di…

Deep Longevity develops deep learning aging clocks for blood, psychological and other data and licenses them through its SenoClock platform…

Elastrin Therapeutics develops targeted therapies that reverse arterial calcification and restore vascular elasticity lost with age.

Fountain Therapeutics uses stem cell assays and machine learning to find drugs that reverse cellular aging, with programs in skin atrophy a…

Generation Lab offers a blood-based SystemAge test that measures biological aging across body systems, built on the aging research of co-fo…

Genflow Biosciences is a London-listed company developing a centenarian SIRT6 gene therapy targeting the aging process in humans and dogs.

Gero uses AI and human longitudinal data to design drugs that treat aging as a system-level failure.

GlycanAge measures biological age from IgG glycans, a test derived from two decades of research linking glycosylation to inflammation and a…

Gordian Biotechnology runs pooled in vivo gene therapy screens with single-cell readouts in animal models of age-related disease to find th…

Immunis develops a stem cell-derived secretome therapy to reverse age-acquired immune decline and related muscle loss.

Integrated Biosciences combines aging biology, chemistry and AI to discover small molecules against age-related disease and aging itself.

Intervene Immune runs the TRIIM-X thymus regeneration trial, following the TRIIM study that reported reversal of epigenetic age in humans.

Junevity develops siRNA therapeutics from its RESET platform that repress transcription factors to reset gene networks altered by aging.

Juvena Therapeutics uses AI to develop protein therapeutics derived from the stem cell secretome to restore regenerative capacity in aging…

Juvenescence is a clinical-stage biotech developing small molecules, biologics and cell therapies that target core mechanisms of aging to t…

Cellular rejuvenation therapeutics

Loyal is a clinical-stage veterinary company developing drugs to extend the healthy lifespan of dogs, led by LOY-002 for senior dogs.

LyGenesis uses lymph nodes as bioreactors to grow ectopic livers and other organs, now in a Phase 2a trial for end-stage liver disease.

Matter Bio develops therapies that preserve genomic integrity by addressing somatic mutations that accumulate with age.

MetroBiotech (Metro International Biotech) develops pharmaceutical NAD+ boosters, led by MIB-626 in Phase 2 trials.

Minovia Therapeutics develops mitochondrial augmentation therapies for mitochondrial disease and positions aging as a mitochondrial disease.

Mitrix Bio grows mitochondria in bioreactors and transplants them to treat age-related decline and extend healthy lifespan.

Epigenetic reprogramming medicines

Oisín Biotechnologies develops non-viral genetic medicines for age-related disease, including senescent cell clearance, klotho and muscle p…

Ora Biomedical screens large compound libraries for lifespan extension in model organisms through its Million-Molecule Challenge to find he…

Rejuve Biotech builds an AI research platform that combines knowledge graphs and neural-symbolic AI to generate and test hypotheses for the…

Rejuvenate Biomed is a Belgian company developing combination drugs for age-related disease, led by RJx-01 in Phase 2 for sarcopenia.

Rejuvenation Technologies develops telomerase mRNA therapeutics intended to reverse aging and prevent age-related disease.

Repair Biotechnologies develops a Cholesterol Degrading Platform to clear localized cholesterol accumulations that drive age-related diseas…

Revel Pharmaceuticals develops therapeutic enzymes that break glucosepane crosslinks and other age-related molecular damage in the extracel…

Senescence-targeted therapeutics

Samsara Therapeutics is an Apollo Health Ventures company developing autophagy-activating drugs for age-related neurodegenerative diseases.

SENISCA develops oligonucleotide therapies that restore splicing factor levels to reprogram senescent cells to a more youthful state.

Shift Bioscience combines single-cell aging clocks and virtual cell models to discover gene targets that rejuvenate aged cells, with lead p…

SIWA Therapeutics develops a monoclonal antibody that targets and removes senescent cells for age-related disease and cancer.

Tolerance Bio develops therapies that restore and preserve thymus function to extend immune healthspan.

TruDiagnostic runs a DNA methylation lab that sells epigenetic biological age tests and develops aging clocks such as OMICmAge and SYMPHONY…

Turn Biotechnologies develops mRNA-based epigenetic reprogramming therapies (ERA platform) to restore cell function lost with age.

Vincere Biosciences develops drugs that enhance mitophagy to counter age-related decline, starting with Parkinson's disease.

YouthBio Therapeutics develops partial cellular reprogramming gene therapies for Alzheimer's disease and other age-related brain diseases.

Aeovian Pharmaceuticals develops selective mTORC1 inhibitors for rare and age-related diseases, led by AV078 for tuberous sclerosis complex.

AgelessRx is a telehealth provider of longevity prescriptions such as rapamycin and metformin that also sponsors decentralized longevity tr…

AgeX Therapeutics was a Michael West company developing induced tissue regeneration and cell therapies for age-related degenerative disease.

Alkahest mines the plasma proteome for therapies and biomarkers of age-related disease, building on young-plasma research.

Dorian Therapeutics was a Stanford spinout developing small-molecule senoblockers that neutralize harmful senescent cells.

Elevian develops GDF11-based and other circulating-factor therapeutics to restore regenerative capacity lost with age.

Emtora Biosciences developed eRapa, an encapsulated rapamycin first created for aging studies at the Barshop Institute, and licensed it to…

Epiterna was a Swiss company that used high-throughput screening to develop drugs extending healthy lifespan in dogs, cats and humans.

Human Longevity runs genomics and imaging based early-detection health assessments marketed for longer life.

InsideTracker sells blood biomarker analysis with an InnerAge biological age score and lifestyle recommendations.

Transforming drug discovery with AI.

Longeveron develops the mesenchymal stem cell therapy laromestrocel for aging-related conditions such as Aging Frailty and Alzheimer's as w…

Optimizing healthspan through preventive medicine.

Oviva Therapeutics develops therapies that improve ovarian function to slow ovarian aging and extend female healthspan.

Renewal Bio builds human embryo models from stem cells with the aim of producing cells and tissues for rejuvenation and transplantation.

resTORbio developed the TORC1 inhibitor RTB101 to improve immune function in older adults, one of the first aging-targeted drugs in late-st…

Satellite Bio develops expandable hepatocyte tissue therapeutics to replace lost liver function in severe liver disease.

Tally Health sells a consumer epigenetic biological age test with supplements and action plans.

Tornado Therapeutics is a Cambrian Bio pipeline company developing next-generation rapalogs to treat disease and extend healthy lifespan.

Biotechnology company targeting aging-related diseases.

The BSRA is a UK charity and learned society that funds and convenes research on the biology of ageing through grants, awards and an annual…

The Dog Aging Institute is a nonprofit that supports research on aging in companion dogs, including the Dog Aging Project.

Fight Aging! is a longevity science and advocacy blog and newsletter, running since 2004, covering rejuvenation biotechnology.

Forever Healthy is a German nonprofit that publishes evidence reviews of longevity interventions and hosts the Rejuvenation Startup Summit…

HEALES is a Belgian nonprofit that informs the public about biogerontology, supports anti-aging research and publishes the monthly newslett…

Human Ageing Genomic Resources maintains curated aging databases such as GenAge, DrugAge, AnAge, CellAge and LongevityMap for the research…

The International Longevity Alliance is a global federation of longevity advocacy groups that promotes research on aging and organizes inte…

The Kitalys Institute is a nonprofit that advances healthspan-extending therapies and runs the Targeting Healthy Longevity series, formerly…

LongeviPAC is a US political action committee that supports candidates backing policies for interventions that extend healthy human lifespa…

Longevity Events organizes Longevity Summit Dublin, an annual science-led conference on aging biology and rejuvenation held at Trinity Coll…

LongX is a nonprofit that trains students and early-career professionals for the longevity field through primer courses and the remote Xplo…

Connecting science and investment in the longevity sector.

Magnitude Biosciences is a contract research company that runs automated C. elegans healthspan and lifespan assays for aging and longevity…

The US federal institute leading and funding research on aging, older adults, and age-related health.

Redefining healthspan through education and research.

The Longevity Forum is a UK not-for-profit that runs an annual forum and London Longevity Week on the science, finance and policy of longer…

The Longevity Prize is a joint prize platform of Foresight Institute, VitaDAO, Methuselah Foundation, Lifespan.io and XPRIZE that runs rese…

The Time Initiative is a fellowship program, run with Amaranth Foundation and AFAR, that funds young researchers to pursue projects in agin…

Aging Analytics Agency publishes reports and dashboards on the longevity industry, investment and biomarker ecosystem as part of Deep Knowl…

The Alliance for Aging Research is a US nonprofit that advocates for research and policy on healthy aging and age-related disease.

GSA is a large interdisciplinary society for aging research whose members and journals include a biological sciences section.

The Healthspan Action Coalition promotes policy and funding for research and innovation that extend healthspan.

Healthy Longevity Clinic is a physician-led longevity clinic that pairs diagnostics with its own clinical research.

The National Academy of Medicine's Healthy Longevity Global Grand Challenge awards prizes to innovations in healthy longevity and hosts an…

Ichor Life Sciences is a preclinical and clinical CRO that offers geriatric animal models and lifespan studies alongside general drug disco…