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Myelin VC is a venture capital firm founded by a group of founders-turned-investors in the United States. Established in 2020, the firm focuses on partnering with visionary entrepreneurs who are developing innovative solutions across various industries. Myelin VC primarily invests in early-stage companies, specifically from seed through Series A funding, with a fund size of $50 million and a portfolio of approximately 50 companies.
The firm has a geographic focus that spans North America, Europe, and Latin America, reflecting its commitment to supporting startups in diverse markets. Myelin VC has achieved notable milestones, including a successful IPO with portfolio company Aura Biosciences. The firm is recognized for its industry-agnostic approach, investing in sectors such as biotech, healthcare, AI, fintech, consumer, climate, food-agtech, mobility, creator-economy, and web3.
Myelin VC's team comprises experienced entrepreneurs who leverage their backgrounds to provide strategic guidance and operational support to portfolio companies. This unique perspective allows them to navigate the challenges of building innovative businesses effectively.
Myelin VC adopts an industry-agnostic investment strategy, focusing on early-stage investments in seed and Series A rounds. The firm seeks to collaborate with outlier founders who are pushing the boundaries of innovation across a wide range of sectors. Their investment criteria encompass biotech, healthcare, AI, fintech, consumer, climate, food-agtech, mobility, creator-economy, and web3.
The check size range for investments typically falls between $250,000 and $3 million, allowing Myelin VC to support startups at various stages of their development. The firm emphasizes the importance of partnering with visionary entrepreneurs who aspire to create a better future through their ideas. Myelin VC's approach is characterized by a willingness to fund unconventional and frontier companies, reflecting their commitment to supporting innovative solutions.
Myelin VC's portfolio includes a diverse array of companies across multiple sectors. Notable portfolio companies include:
Matías Nisenson - General Partner. Matías is a 2x founder with experience in blockchain gaming and co-founder of DeFi Wonderland. He brings a strong entrepreneurial background to Myelin VC.
Martin Varsavsky - General Partner. Martin is a serial entrepreneur known for founding Jazztel, FON, and Prelude Fertility. His extensive experience in building successful companies informs his investment strategy.
Alec Oxenford - Non-Executive General Partner. Alec is the founder of OLX, a classified ads platform operating in over 30 countries. His expertise in scaling businesses is a valuable asset to the firm.
Federico Jack - Investment Partner. Federico has a background in venture capital and entrepreneurship, focusing on identifying promising startups for investment.
Gaston Maffei - Principal. Gaston plays a key role in sourcing and evaluating potential investments, leveraging his experience in the startup ecosystem.
Catalina Plorutti - Chief Financial Officer. Catalina oversees the financial operations of Myelin VC, ensuring sound financial management and reporting.
Milos Fulton - Venture Partner. Milos brings a wealth of experience in venture capital and startup growth, contributing to the firm's investment decisions.
Cesar Levene - General Partner. Cesar has a strong background in entrepreneurship and venture capital, focusing on supporting innovative startups.
To pitch Myelin VC, founders should visit their website at myelin.vc. It is advisable to include a comprehensive pitch deck that outlines the business model, market opportunity, competitive landscape, and team background. Myelin VC prefers warm introductions but will also consider direct applications through their website.
Response times can vary, but founders can generally expect to hear back within a few weeks. The firm encourages clear and concise communication in the pitch materials to facilitate the review process.
In May 2025, Myelin VC made a notable investment in Throne, a startup focused on gut health AI. This investment reflects the firm's commitment to supporting innovative solutions in the health sector.
In November 2024, Myelin VC led a $4 million seed extension for Nodal, a company specializing in surrogacy services. This investment highlights the firm's interest in unconventional and frontier companies.
In September 2024, Myelin VC invested over $5 million in Longshot Space, a company innovating in space launch technologies. This deal underscores the firm's willingness to fund unconventional ventures.
Myelin VC has also been active in supporting its portfolio companies, with Aura Biosciences achieving an IPO and NUE Life and Apryl being acquired, showcasing the firm's successful investment strategy.
What are Myelin VC's investment criteria?
Myelin VC invests in early-stage companies, focusing on seed and Series A funding. They seek outlier founders developing innovative solutions across various sectors, including biotech, healthcare, AI, fintech, and more.
How can I pitch to Myelin VC?
Founders can pitch to Myelin VC through their website at myelin.vc. It is recommended to include a clear overview of the business model, market opportunity, and team background in the pitch deck.
What makes Myelin VC different from other venture capital firms?
Myelin VC is founded by entrepreneurs who have built and exited companies themselves. This experience allows them to provide unique insights and operational support to portfolio companies, differentiating them from traditional investors.
What is the geographic scope of Myelin VC's investments?
Myelin VC invests in startups across North America, Europe, and Latin America, reflecting their commitment to supporting diverse markets and innovative solutions globally.
What is the typical check size for investments?
Myelin VC typically invests between $250,000 and $3 million in their portfolio companies, allowing them to support startups at various stages of growth.
What kind of post-investment involvement does Myelin VC have?
Myelin VC provides strategic guidance, industry connections, and operational support to help founders navigate the challenges of building their businesses after investment.
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