Microbiome

Metagenomic sequencing catalogs all microorganisms in a sample. Metabolomics measures the chemical outputs of microbial communities. Defined microbial consortia use selected bacterial strains rather than entire fecal transplants. Precision prebiotics feed specific beneficial bacteria. Computational models predict microbiome-drug interactions. Synthetic biology engineers microbes with therapeutic functions.

Live biotherapeutics treat recurrent C. difficile infection. Microbiome testing informs personalized nutrition and supplement recommendations. Microbiome analysis predicts cancer immunotherapy response. Agricultural microbiome products reduce synthetic fertilizer dependence.

The global microbiome therapeutics market is projected to reach $2+ billion by 2030, with the broader microbiome market (including diagnostics, consumer testing, and dietary products) significantly larger. FDA approval of Rebyota and Vowst validated the therapeutic category.