Most active VC investors in generative AI 2026

Most active VC investors in generative AI 2026 by PitchBook: 10 venture firms ranked, led by Sequoia. Full list with movement since the last edition and method...

See the original list at PitchBook

Sequoia is first for the fourth year in a row with 164 deals, four ahead of Andreessen Horowitz (160, up from 4th). Transpose Platform Management is the only new entrant (8th); Gaingels fell from 2nd to 9th and Antler rose from 10th to 6th.

Article updated July 27, 2026 after first publication on July 10, 2026.

The full list

Rank	Name	Location	Since 2025
1	SequoiaExits: 15 · Deal count: 164 · Previous rank: 1 · Median deal size usd m: 28.45	Menlo Park, CA	No change
2	Andreessen HorowitzExits: 8 · Deal count: 160 · Previous rank: 4 · Median deal size usd m: 30	Menlo Park, CA	Up 2
3	Pioneer FundExits: 6 · Deal count: 140 · Previous rank: 3 · Median deal size usd m: 4.8	San Francisco	No change
4	General CatalystExits: 12 · Deal count: 110 · Previous rank: 8 · Median deal size usd m: 40	San Francisco	Up 4
5	Alumni VenturesExits: 9 · Deal count: 107 · Previous rank: 7 · Median deal size usd m: 11.5	Manchester, NH	Up 2
6	AntlerExits: 1 · Deal count: 107 · Previous rank: 10 · Median deal size usd m: 0.2	Singapore	Up 4
7	Khosla VenturesExits: 10 · Deal count: 97 · Previous rank: 5 · Median deal size usd m: 25	Menlo Park, CA	Down 2
8	Transpose Platform ManagementExits: 0 · Deal count: 95 · Median deal size usd m: 6.3	San Francisco
9	GaingelsExits: 9 · Deal count: 92 · Previous rank: 2 · Median deal size usd m: 8	New York City	Down 7
10	LightspeedExits: 6 · Deal count: 86 · Previous rank: 9 · Median deal size usd m: 56.7	Menlo Park, CA	Down 1

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PitchBook: Most active VC investors in generative AI 2026