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Most active VC investors in AI agents 2025

Most active VC investors in AI agents 2025 by PitchBook: 10 venture firms ranked, led by Y Combinator. Full list with movement since the last edition and method...

Publisher
PitchBook
Published
December 23, 2025
On this page
10 of 10 ranked
Method
Data
Reliability
Grade B

Y Combinator (47 deals) edges Sequoia Capital (46), with Andreessen Horowitz third on 31. Three firms tie on 19 deals at the bottom of the list.

The full list

RankNameLocation
1Y CombinatorDeal count: 47 · Median deal size usd m: 7Mountain View, CA
2Sequoia CapitalDeal count: 46 · Median deal size usd m: 23.7Menlo Park, CA
3Andreessen HorowitzDeal count: 31 · Median deal size usd m: 19.4Menlo Park, CA
4Pioneer FundDeal count: 28 · Median deal size usd m: 4.2San Francisco, CA
5General CatalystDeal count: 24 · Median deal size usd m: 73.52San Francisco, CA
6AntlerDeal count: 22 · Median deal size usd m: 0.16Singapore
7Lightspeed Venture PartnersDeal count: 21 · Median deal size usd m: 106.5Menlo Park, CA
=8AccelDeal count: 19 · Median deal size usd m: 8.42Palo Alto
=9Index VenturesDeal count: 19 · Median deal size usd m: 50London
=10Alumni VenturesDeal count: 19 · Median deal size usd m: 17.9Manchester, NH

This list is reproduced as PitchBook published it. Names are shown as printed. The ranking belongs to its publisher.

Sources and known limits

A reviewed date is not available for this page.