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Siryo S.p.A. is a venture capital firm founded in Bari, Italy, focusing on disruptive technologies in materials science. Established to enhance both human and environmental health, the firm employs a One-Health approach. This strategy supports researchers and teams in transitioning their laboratory innovations into market-ready solutions. Siryo provides both financial backing and operational tools to facilitate this process.
The firm manages a total capital of €45 million and operates a single fund. Siryo has a portfolio of eight companies, reflecting its commitment to investing in innovative technologies. The team consists of five members, including prominent figures such as Prof. Alessandro Sannino, who serves as Chairman. Siryo's office is located at Piazza Giuseppe Massari, 19, 70122 Bari, Italy.
Over the years, Siryo has established itself as a key player in the venture capital landscape, particularly in Southern Europe, North Africa, and the Middle East. The firm has been active in organizing events to promote innovation, such as the
Siryo S.p.A. invests in innovative technologies across several sectors, including healthcare, energy, food-agtech, and biotech. The firm employs a modern Venture Studio approach, which incorporates structured selection processes and active management support. This model allows Siryo to target various investment stages, including Friends & Family, Angel, Accelerator, Seed, and Seed+ (Extension) rounds.
The firm primarily focuses on the Southern European, Middle Eastern, and North African markets. Siryo's investment strategy emphasizes disruptive technologies that align with its One-Health thesis, which aims to improve human and environmental health. The firm seeks startups that demonstrate strong potential for growth and innovation, particularly those that can navigate the complexities of bringing new technologies to market.
Siryo S.p.A. has a diverse portfolio comprising eight companies, each contributing to its focus on innovative technologies. Notable portfolio companies include:
These companies reflect Siryo's commitment to enhancing human and environmental health through disruptive technologies. The firm actively supports its portfolio companies with financial resources and operational expertise, facilitating their growth and market entry.
Prof. Alessandro Sannino - Chairman. He has a background in materials science and is known for his research in hydrogels and biomaterials, previously associated with the University of Naples and the University of Leeds.
Dott. Lucio Luigi Gaita - Vice Chairman - Independent. He brings extensive experience in venture capital and corporate governance.
Avv. Paolo De Carlo - Board Member. He has a legal background with expertise in corporate law and venture financing.
Dott. Raffaele Bruni - Board Member - Independent. He has a strong background in finance and investment management.
Dott.ssa Katia Valerio - Board Member - Independent. She specializes in innovation and technology transfer, contributing valuable insights to the board.
To pitch to Siryo S.p.A., startups should submit their proposals through the firm's website at Siryo Pitch Submission. The pitch deck should include a clear overview of the business model, market analysis, and financial projections. Siryo prefers warm introductions but will consider direct submissions. Response times may vary, but founders can expect feedback within a few weeks.
In February 2026, Siryo S.p.A. organized the "Investire nell'Innovazione" event at Confindustria Bari-BAT. This event was held in collaboration with AIFI, the Italian Private Equity and Venture Capital Association, and Assoprevidenza. The event featured participation from pension funds, EU development entities, and universities, highlighting Siryo's active role in the Italian venture capital ecosystem.
Siryo continues to engage with the startup community, emphasizing its commitment to supporting innovative technologies that enhance human and environmental health. The firm remains focused on its One-Health approach, facilitating the transition of laboratory innovations to market-ready solutions.
What are Siryo's investment criteria?
Siryo S.p.A. invests in innovative technologies across sectors such as healthcare, energy, food-agtech, and biotech. The firm targets various stages of investment, including Friends & Family, Angel, Accelerator, Seed, and Seed+ (Extension).
How can startups apply or pitch to Siryo?
Startups can pitch to Siryo by submitting their proposals through the firm's website at Siryo Pitch Submission. Interested parties can also reach out via email at info@siryo.it.
What makes Siryo different from other venture capital firms?
Siryo S.p.A. distinguishes itself through its One-Health approach, focusing on disruptive technologies that enhance both human and environmental health. The firm employs a modern Venture Studio model, providing structured support and active management to its portfolio companies.
What is the typical check size for investments?
Siryo typically invests between €500K and €10M in its portfolio companies, depending on the stage and needs of the startup.
What geographic areas does Siryo focus on?
Siryo primarily invests in Southern Europe, the Middle East, and North Africa, targeting innovative startups within these regions.
What kind of post-investment support does Siryo provide?
Siryo adds value to its portfolio companies by offering operational tools and management expertise, helping them navigate the complexities of bringing innovative technologies to market.
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