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New Leaf Venture Partners (NLVP) is a venture capital firm founded in 2005 and headquartered in New York City. The firm emerged from the healthcare team of Sprout Group, establishing itself as a credible player in the healthcare investment space. NLVP has a strong focus on advancing healthcare through investments in innovative companies that deliver clinically significant and commercially viable solutions.
As of now, NLVP manages over $1 billion in assets under management (AUM) and has invested more than $2 billion across 150+ companies since its inception. The firm has achieved notable milestones, including 38 public exits and the creation of 18 unicorns within its portfolio. NLVP operates with a dual-vehicle structure, comprising the NLV-III core venture fund and the NLV Growth-I fund, which targets growth-stage private and public biopharma companies.
New Leaf Venture Partners specializes in healthcare investments, targeting various stages of company development, from early-stage ventures to public offerings. The firm emphasizes sectors such as biopharmaceuticals, healthcare IT/data, life science tools, and select medical devices. NLVP's investment strategy is centered on identifying disruptive healthcare technologies that have the potential to revolutionize the healthcare system.
NLVP seeks visionary teams and businesses that are at the forefront of biology and innovation. The firm is particularly interested in companies that are developing transformative solutions that enhance healthcare delivery and outcomes. This focus on innovation is reflected in their portfolio, which includes companies that are making significant strides in the healthcare sector.
New Leaf Venture Partners has a diverse portfolio of companies within the healthcare sector. Notable portfolio companies include:
These companies exemplify NLVP's commitment to investing in businesses that are transforming healthcare through innovation and technology.
Ron Hunt: Co-Founder and Managing Director at NLVP, Ron has extensive experience in healthcare investing and has been instrumental in the firm's growth since its inception.
Vijay Lathi: Co-Founder and Managing Director, Vijay brings a wealth of knowledge in venture capital and healthcare, contributing to NLVP's strategic direction.
Craig Slutzkin: Chief Operating Officer and Chief Financial Officer, Craig oversees the firm's operations and financial management, ensuring efficient fund deployment.
Anthony Ford: Senior Advisor, Anthony provides strategic insights and guidance, leveraging his extensive network in the healthcare industry.
To pitch New Leaf Venture Partners, founders should submit their proposals through the firm's website. A well-structured pitch deck should include details about the business model, market opportunity, competitive landscape, and team qualifications. Founders are encouraged to provide a clear narrative about their innovation and its potential impact on the healthcare sector.
New Leaf Venture Partners is involved in the NY Digital Health Accelerator, which supports digital health startups by providing mentorship, resources, and access to a network of industry experts. Startups interested in this program can apply through the accelerator's website for eligibility and application details.
As of March 2026, New Leaf Venture Partners continues to operate as a leading healthcare-focused venture capital firm. The firm has not announced any recent fund raises or significant leadership changes, indicating a potential quiet period as they deploy existing capital.
What are New Leaf Venture Partners' investment criteria?
NLVP focuses exclusively on healthcare-related companies, targeting sectors such as biotechnology, pharmaceuticals, medical devices, and healthcare services. The firm invests across various stages, from early ventures to growth and public offerings.
How can founders apply or pitch to NLVP?
Founders can pitch their ideas through the firm's website at nlvpartners.com. It is advisable to include a comprehensive overview of the business model, market opportunity, and team background in the pitch deck.
What makes New Leaf Venture Partners different from other VCs?
NLVP is distinguished by its exclusive focus on healthcare investments and its dual-vehicle structure, which allows for flexibility in funding both early-stage and growth-stage companies. The firm has a proven track record with over 38 IPOs and 18 unicorns.
What is the geographic scope of NLVP's investments?
New Leaf Venture Partners primarily invests in companies based in the United States, focusing on innovative healthcare solutions that can have a significant impact on the industry.
What kind of post-investment involvement does NLVP have?
NLVP actively engages with its portfolio companies, providing operational support, strategic guidance, and access to its extensive network within the healthcare sector.
What is the typical check size for investments made by NLVP?
While specific check sizes are not disclosed, NLVP invests across various stages, which typically involves significant capital for both early-stage and growth-stage companies.
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