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Cultivation Capital is a St. Louis-based VC firm founded in 2012 by Brian Matthews, Cliff Holekamp, Jim McKelvey, Kyle Welborn, Peter Esparrago, and Rick Holton Jr. Family of funds focused on early-stage investing. 48 team members, 31 partners.
Life Sciences & Health Technology, Software & IT, Agriculture Technology, and Geospatial Technology. Seed through Series B. Initial checks $100K-$3.5M.
155 companies, 1 unicorn, 2 IPOs, 33 acquisitions. Leads ~50% of rounds. Notable: WellSky, Planful, Sharpen, DealCloud. Recent: Hydrosat Series B (Jan 2026).
To approach Cultivation Capital, founders should visit their contact page or reach out via email at info@cultivationcapital.com. They are particularly interested in companies that have the potential to transform industries.
Recently, Cultivation Capital has been active in the startup ecosystem, leading a $2.2 million investment in Force Equals and participating in various funding rounds, including a $4.25 million seed round for Bluprynt. Their portfolio continues to grow, with 155 companies and notable exits such as WellSky and Planful.
Cultivation Capital invests in Seed and Series A stages, focusing on early-stage companies.
You can pitch Cultivation Capital by visiting their contact page or emailing them at info@cultivationcapital.com.
The firm focuses on sectors including SaaS, healthcare, generative AI, food agtech, and space tech.
Cultivation Capital typically invests between $100,000 and $3 million in startups.
Cultivation Capital invests in North America, the United States, and globally, with a commitment to building an inclusive portfolio.
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