InvestorStart-Up Chile is a government-backed accelerator program established in 2010, designed to attract global entrepreneurial talent and foster innovation…
The startup scene in Chile
StartupBlink’s September 2026 profile ranked Santiago 72nd globally and first in Chile, using scores based on investment, employee count, and quarterly web traffic, according to the publisher. Bloomberg Línea reported that NotCo developed plant-based food technology in a Santiago laboratory in 2021; that year, it also reported a $1.5 billion company valuation and a $235 million financing round. [29680, 29685, 29686]
About
StartupBlink’s September 2026 profile ranked Santiago 72nd globally and first in Chile, using scores based on investment, employee count, and quarterly web traffic, according to the publisher. Bloomberg Línea reported that NotCo developed plant-based food technology in a Santiago laboratory in 2021; that year, it also reported a $1.5 billion company valuation and a $235 million financing round. [29680, 29685, 29686]
UC’s BRAIN Chile links UC innovation and technology-transfer units with Banco Santander to support university-connected science ventures from laboratory results through prototypes at TRL 3–5. The inspected page did not state a current intake window. [29688]
CORFO identifies Buk as a Chilean HR software startup and a Start-Up Chile alum from 2018, and reported its valuation as $850 million in April 2025. [29682]
Startup ecosystem standing
Where Santiago ranks
| Ranking | Edition | Listed as | Position | Since last edition | Trust | What it measures |
|---|---|---|---|---|---|---|
 Global Startup Ecosystem Report (GSER) | Startup Ecosystem Report 2012 | Santiago | #20 | No prior edition | C | Ecosystem, Performance, Finance, Talent, Innovation |
 Global Startup Ecosystem Index (cities) | 2025 | Santiago | #75 | No prior edition | B | Ecosystem, Activity, Finance, Business Climate |
 Global Financial Centres Index | GFCI 40 | Santiago | #98 | No prior edition | B | Finance, Competitiveness, Business Climate |
| Emerging Ecosystems Ranking (GSER Top 100) | 2026 | Santiago-Valparaiso | 51 to 60 | No prior edition | C | Ecosystem, Performance, Finance, Talent |
48 organizations with a profile
Who's based in Santiago
Investors 38
Investor
InvestorLeading investment bank in Latin America, specializing in diverse financial services.
InvestorFinancing solutions for businesses through factoring.
The 3 most prominent of 38. Browse all investors
Venture studios 5
Venture studioCreating AI-native companies for operational excellence.
Venture studioCreating and accelerating startups in Chile.
Venture studioFostering innovation in banking through startup collaboration.
The 3 most prominent of 5. Browse all venture studios
Incubators 3
IncubatorIncubator for high-growth technology startups.
IncubatorEmpowering entrepreneurs through strategic consulting and incubation.
IncubatorEmpowering technology ventures in Latin America.
Accelerators 2
AcceleratorAccelerating technology-driven startups to Series A.
AcceleratorEmpowering entrepreneurs through effective communication.
Pick what describes you
Your way in
Raising in Santiago
Investors based here, and the programs that take teams at your stage.
Get investor introsFinding startups in Santiago
Accelerators and incubators here see the earliest teams first.
Get startups that fitScouting in Santiago
Campuses and communities are where teams form before anyone funds them.
Start scoutingFrom public sources
What the sources say about Santiago
EL PAÍS describes EtM's annual event, recurring pitch and networking sessions, and ecosystem talks as routes for connecting ecosystem actors.
Source: Emprende tu Mente avanza en la conexión de los emprendedores con los inversionistas y las grandes empresasThe official event page lists November 19-21 at Parque Bicentenario, Vitacura and links to ticket purchase.
Source: EtMday 2026: El evento de Emprende tu MenteBRAIN Chile links UC's innovation and transfer units with Banco Santander to accelerate university-connected science ventures from laboratory results through TRL 3-5 prototypes; current intake is unstated.
Source: Aceleración y financiamientoBloomberg Línea reported a $1.5 billion valuation and $235 million financing round for NotCo in 2021.
Source: CEO de NotCo: “Ser unicornio es extremadamente potente para el ecosistema”Bloomberg Línea reported in 2021 that NotCo developed its plant-based food technology in a Santiago laboratory.
Source: CEO de NotCo: “Ser unicornio es extremadamente potente para el ecosistema”EL PAÍS argued that Chile needs follow-on capital and stronger early customer demand alongside CORFO support.
Source: De los unicornios al letargo: ¿qué pasó con la innovación en Chile?
Questions about Santiago
How does Santiago rank as a startup ecosystem?
Santiago is #75 of 1,473 in StartupBlink Index (cities) (2025). It appears in 4 published rankings; the table above lists each one.
How many startup investors are based in Santiago?
38 investors based in Santiago have a profile here, including Start-Up Chile, BTG Pactual Chile and BL Capital Factoring. The real number is higher.
Are there accelerators or incubators in Santiago?
Yes. Santiago has 2 accelerators, 3 incubators and 5 venture studios on record, including Discovery-A, Cidif Digital Ventures and MindColab.
Geographic proximity
Nearby cities to Santiago
City
103 km away
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