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The startup scene in United States

Startup Louisville’s portal displayed over 735 events, 243 organizers, and 257 venues when checked on October 2, 2026; these are portal counters, not a full regional census. [Claim 36884]

Population
243,639
Time zone
America/Kentucky/Louisville
Fig. 958 · American bison

About

Startup Louisville’s portal displayed over 735 events, 243 organizers, and 257 venues when checked on October 2, 2026; these are portal counters, not a full regional census. [Claim 36884]

Kentucky’s economic development agency reports that Appriss was headquartered in Louisville from its 1994 inception and used data analytics to address safety, fraud, risk, and compliance needs across government, retail, healthcare, and public safety; a later headquarters expansion was in Jeffersontown in the Louisville metro. [Claim 36887] Startup Louisville reports that Appriss began in Louisville in 1994 and developed VINE, a victim custody-status notification system. [Claim 36888]

The Community Foundation of Louisville’s 2026 Vogt Awards offered up to six early-stage firms up to $25,000 and a 10-week accelerator. Applications opened May 8 and closed June 5, 2026; the cycle was closed as of October 2, 2026. [Claim 36886]

Startup ecosystem standing

Where Louisville ranks

Rankings that list Louisville
RankingEditionPositionSince last editionTrustWhat it measures
Global Startup Ecosystem Index (cities)2025#140No prior editionBEcosystem, Activity, Finance, Business Climate
Positions come from each publisher's edition. Open a ranking for its method and trust notes, or an edition for the full list.

34 organizations with a profile

Who's based in Louisville

Investors 23

Venture First logoInvestor

Empowering growth-focused companies with capital and expertise.

The 3 most prominent of 23. Browse all investors

Accelerators 5

Aging2.0 logoAccelerator

Accelerating innovation in aging and healthcare.

The 3 most prominent of 5. Browse all accelerators

Incubators 4

Walnut St. Labs logoIncubator

Empowering startups through marketing and product development.

The 3 most prominent of 4. Browse all incubators

Venture studios 2

Cassilly Capital logoVenture studio

Innovating industries through strategic partnerships.

Pick what describes you

Your way in

From public sources

What the sources say about Louisville

Questions about Louisville

How does Louisville rank as a startup ecosystem?

Louisville is #140 of 1,473 in StartupBlink Index (cities) (2025).

How many startup investors are based in Louisville?

23 investors based in Louisville have a profile here, including Chrysalis Ventures, Venture First and Access Ventures. The real number is higher.

Are there accelerators or incubators in Louisville?

Yes. Louisville has 5 accelerators, 4 incubators and 2 venture studios on record, including Aging2.0, The Shop One Stop and Cassilly Capital.

Geographic proximity

Nearby cities to Louisville

All cities in United States

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