25madison

25madison is a New York-based venture studio and investment platform that specializes in leveraging artificial intelligence (AI) to modernize traditional industries. Founded in 2025, the organization focuses on early-stage venture capital, incubating and investing in AI-native software and technology-enabled businesses. With a commitment to enhancing operational efficiencies, 25madison also engages in transformation buyouts of lower-middle market businesses, aiming to drive innovation and growth through applied AI.

The primary focus of 25madison is to invest in early-stage venture opportunities, particularly in AI-native software and technology-enabled businesses. The organization provides incubation services and transformation buyouts, emphasizing the application of AI to improve operational efficiencies and modernize legacy industries. Their investment strategy is centered around identifying and nurturing category-defining startups in the B2B software and healthcare sectors.

25madison offers a unique combination of venture funding, incubation services, and operational expertise. Founders can expect access to a network of industry professionals, mentorship, and resources to accelerate their business growth. The organization also provides pathways for customer access and acquisition through its private-equity relationships.

Q: What stages does 25madison invest in? A: 25madison invests in pre-seed to Series A stages. Q: How can I apply for funding? A: Applications are accepted through the website at https://www.25madison.com/apply. Q: What sectors does 25madison focus on? A: The organization focuses on B2B software, healthcare, AI-native software, supply chain, and industrials.