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Truffle Capital is an independent venture capital firm founded in 2001 and based in Paris, France. The firm specializes in financing innovation in the biomedtech and fintech sectors, managing approximately €500 million in assets under management (AUM). Over its two decades of operation, Truffle Capital has backed 79 companies, achieving significant exits including multiple IPOs on Euronext.
Founded by Philippe Pouletty and Bernard-Louis Roques, Truffle Capital has raised over €1.2 billion since inception. The firm has a strong focus on European companies with global potential, emphasizing radical innovations that can disrupt traditional markets. Their notable milestones include a history of successful exits, with 46 total exits and 15 IPOs.
Truffle Capital invests primarily in two core verticals: life sciences and fintech. In the life sciences sector, the firm emphasizes medtech, biotech, and digital health innovations. In fintech, Truffle Capital focuses on proprietary technologies such as AI, blockchain, and cybersecurity solutions tailored for financial institutions. The firm typically invests between €5 million and €15 million per company, targeting startups with at least €5 million in recurring revenue and robust growth strategies.
Truffle Capital acts as a lead investor, often taking significant stakes in its portfolio companies. The firm is particularly interested in European startups that demonstrate global scalability and disruptive potential. Their investment strategy is designed to support companies that are poised to make a substantial impact in their respective fields.
Truffle Capital's portfolio includes 79 companies, with notable successes and exits. Key portfolio companies include:
Philippe Pouletty, M.D. - CEO & Co-Founder. Philippe has extensive experience in the life sciences sector and has led numerous successful investments.
Bernard-Louis Roques - CEO & Co-Founder. Bernard-Louis has a strong background in venture capital and has been instrumental in the firm's growth.
Henri Moulard - Chairman & Co-Founder. Henri brings a wealth of experience in corporate governance and strategic oversight.
Antoine Pau - Senior Partner, BioMedTech. Antoine specializes in medical technology investments and has a strong track record in the sector.
Alain Chevallier - Senior Partner, BioMedTech. Alain focuses on biotech investments and has significant expertise in the field.
François Romaneix - Senior Partner, BioMedTech. François has a deep understanding of the regulatory landscape in life sciences.
Vincent Dagommer - Operating Partner, BioMedTech. Vincent provides operational support to portfolio companies in the medtech space.
Fanny Brugiere - Director of Investor Relations. Fanny manages relationships with investors and stakeholders.
Olivier Huon - Chief Financial Officer. Olivier oversees the financial operations of the firm.
To pitch to Truffle Capital, startups should use the contact form available at truffle.com/en/contact/. It is recommended to include a comprehensive pitch deck that outlines the business model, market opportunity, and financial projections. Response times may vary, but founders should expect to hear back within a few weeks.
Truffle Capital operates a BioMedTech Accelerator, established in 2017. This program supports the growth of companies in the medical technology sector by fostering collaboration among startups and providing access to expertise and resources necessary for scaling.
On October 1, 2025, Truffle Capital made its latest investment, continuing its active engagement in the market. In the past 12 months, the firm has completed five investments, further expanding its portfolio in the biomedtech and fintech sectors.
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What are Truffle Capital's investment criteria?
Truffle Capital primarily invests in the biomedtech and fintech sectors, targeting companies with at least €5 million in recurring revenue and robust growth strategies. They typically invest between €5 million and €15 million.
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How can startups apply or pitch to Truffle Capital?
Startups can pitch to Truffle Capital through their contact page at truffle.com/en/contact/. It is advisable to include a detailed business plan and financial projections in the pitch.
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What makes Truffle Capital different from other venture capital firms?
Truffle Capital has a strong focus on disruptive innovations in life sciences and fintech, with deep sector expertise and a history of successful exits, including multiple IPOs.
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What is Truffle Capital's geographic scope?
The firm primarily invests in European companies, particularly those based in Western Europe and France, with a focus on startups that have global potential.
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What is Truffle Capital's post-investment involvement like?
Truffle Capital actively supports its portfolio companies through strategic guidance, access to their extensive network, and expertise in navigating regulatory pathways and public market IPOs.
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