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SOSV is a global, multi-stage venture capital firm founded in 1995 by Sean O'Sullivan. Headquartered in Princeton, New Jersey, the firm has expanded its presence with offices in New York City, Newark, San Francisco, Cork (Ireland), Pune (India), Shenzhen (China), and Tokyo (Japan). As of April 2024, SOSV manages $1.5 billion in assets under management (AUM) and has funded over 961 companies, including five unicorns and six IPOs.
The firm operates two primary startup development programs: HAX, which focuses on hard tech, and IndieBio, which specializes in biotech. SOSV's portfolio includes notable companies such as DraftKings, Getaround, and VideoVerse, with a strong emphasis on sectors that drive human and planetary health. The firm has a dedicated team of over 80 staff members and 10 general partners, ensuring comprehensive support for its portfolio companies.
SOSV's investment strategy is centered on deep tech startups that create tangible solutions for pressing global issues. The firm primarily invests in sectors such as climate tech, health tech, physical AI, robotics, industrial automation, and biotech. Initial investments typically range from $250,000 to $550,000 at the pre-seed stage, with follow-on investments available through a $100 million Select Fund.
Geographically, SOSV operates globally, with a significant presence in the United States, India, Europe, and Southeast Asia. The firm is recognized as a leading investor in climate tech, boasting a portfolio valuation of $11.09 billion in this sector alone. SOSV's approach emphasizes hands-on support through its HAX and IndieBio programs, which provide engineering, manufacturing, and design resources to help founders scale their businesses effectively.
SOSV's portfolio includes over 961 companies, with a focus on deep tech innovations. Notable companies in their portfolio include:
Recent investments include Tidal Vision ($46.7 million), Prolific Machines ($54.6 million), unSpun ($32 million), Windfall Bio ($28 million), and Simbe Robotics ($50 million). The firm has a strong track record with five unicorns, six IPOs, and 64 acquisitions, demonstrating its ability to identify and support high-potential startups.
Sean O'Sullivan - Managing General Partner. Founder of SOSV with extensive experience in venture capital and deep tech investments.
Stephen Chambers, PhD - General Partner. Holds a PhD and brings expertise in technology commercialization and startup development.
Deborah Zajac - General Partner. Experienced in venture capital with a focus on health tech investments.
Sabriya Stukes, PhD - Chief Science Officer. Provides scientific expertise and guidance for biotech investments.
Duncan Turner - Managing Director & General Partner. Focuses on hard tech investments and operational support for portfolio companies.
Avra van der Zee - General Partner. Specializes in early-stage investments and startup scaling strategies.
To pitch SOSV, founders should submit their applications through the online portal at sosv.com/will-sosv-invest-in-your-company/. The pitch deck should include a clear overview of the business model, market opportunity, and team qualifications. SOSV prefers warm introductions but also accepts direct applications. Response times may vary, but the firm is known for being highly active in deploying capital.
SOSV operates the following programs to support its portfolio companies:
These programs are designed to equip founders with the necessary tools and resources to scale their businesses effectively.
On February 5, 2026, SOSV made its most recent investment in Deep Root Biolabs, continuing its trend of active engagement in the deep tech sector. In the past 12 months, the firm has completed 21 investments, showcasing its commitment to supporting innovative startups. SOSV closed its latest fund, SOSV V, in April 2024, raising $306 million to further enhance its investment capabilities.
Q?
What are SOSV's investment criteria?
SOSV focuses on deep tech startups that address significant global challenges, particularly in climate tech, health tech, and physical AI. The firm primarily invests at the pre-seed stage, with initial checks ranging from $250,000 to $550,000.
Q?
How can I apply or pitch to SOSV?
Founders can apply through SOSV's application page at sosv.com/apply or contact them via email at contact@sosv.com.
Q?
What makes SOSV different from other venture capital firms?
SOSV distinguishes itself through its dual model of venture capital and accelerator programs, providing extensive resources and support to startups through HAX and IndieBio.
Q?
What is the geographic scope of SOSV's investments?
SOSV invests globally, with a significant presence in the United States, India, Europe, and Southeast Asia, supporting founders from diverse backgrounds.
Q?
What is the typical follow-on investment size?
Follow-on investments can reach up to $100 million through SOSV's Select Fund, allowing for significant support as companies scale.
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