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Scientifica is an Italian venture capital organization founded in 2021, dedicated to promoting scientific innovation and responsible investment practices within the European technology landscape. The firm is headquartered in Italy and operates with a commitment to integrity, transparency, and respect. Scientifica has established a unique operational model that integrates capital with specialized expertise and advanced technological infrastructure, including its own laboratory hub located in L'Aquila.
As of now, Scientifica manages a fund size of €200 million and has invested in 16 companies across various stages of development. The organization has expanded its presence with offices in Rome, London, and a strategic operational hub in Silicon Valley. Notable milestones include the launch of specialized investment vehicles such as Scientifica Fund 1 and Quantum Italia, aimed at supporting startups in deep tech sectors.
Scientifica focuses on deep tech sectors, emphasizing advanced technologies that leverage Italy's strong research base and patent portfolio. The firm invests in a wide range of sectors, including Artificial Intelligence, Quantum Technologies, BioTech, HealthTech, ClimateTech, Advanced Materials, and Industrial Tech. Their investment strategy encompasses various stages, from Friends & Family and Angel rounds to Series A through Series F and Growth Equity, with check sizes ranging from $50,000 to $500,000.
Scientifica supports startups at different stages of development, from initial ideas to scale-up phases, utilizing specialized investment vehicles like Scientifica Fund 1 and Quantum Italia. The firm seeks to partner with founders who demonstrate a strong commitment to scientific innovation and responsible practices, aiming to foster collaboration and innovation within its portfolio through access to laboratory facilities and specialized expertise.
Scientifica's portfolio includes a diverse range of companies across various deep tech sectors. Notable portfolio companies include:
Patrick Leoni Sceti - General Partner. He has extensive experience in venture capital and has led multiple successful investments in deep tech sectors.
Riccardo D'Alessandri - Managing Partner Operational. He oversees the operational aspects of the firm and has a strong background in managing venture capital funds.
Simone Valorani - Head of Strategy & Operations. He is responsible for strategic planning and operational efficiency within the organization.
Jacopo Santin - Portfolio Manager. He manages the firm's investment portfolio and works closely with portfolio companies to drive growth.
Giuliana Lilli Gallo - Investor Relations Manager. She handles communications with investors and stakeholders, ensuring transparency and engagement.
Davide Coletti - Senior Investment Manager. He focuses on sourcing and evaluating new investment opportunities.
Giulio Piccione - Senior Investment Associate. He supports the investment team in due diligence and portfolio management.
Samuele Troiano - Senior Investment Analyst. He conducts market research and analysis to inform investment decisions.
Manuel Casciano - Investment Associate. He assists in the evaluation of potential investments and portfolio support.
Pietro Fontana - Business Operations Analyst. He manages operational processes within the firm.
Lucilla Mazzeo - Dealflow & Scouting Specialist. She identifies and evaluates potential investment opportunities.
Andrea Di Placido - Open Innovation Analyst. He focuses on fostering innovation within the portfolio.
Flaminia Feleppa - Dealflow Analyst. She supports the dealflow process and assists in investment evaluations.
Roberto Colagrossi - Tenders & Grants Manager. He manages grant applications and funding opportunities.
Serena Valente - Tenders & Grants Assistant. She supports the tenders and grants process.
Ilaria Angeloni - Head of Finance. She oversees the financial operations of the firm.
Lucia Cittadino - Administrative Officer. She manages administrative tasks within the organization.
Roberta Biggio - Talent Manager. She focuses on talent acquisition and management.
Carmen Cabrera - Head of Marketing & Communication. She manages the firm's marketing and communication strategies.
Alessandra De Nichilo - Social Media Specialist. She handles the firm's social media presence.
Federica Blasini - Art Director. She oversees the visual aspects of the firm's branding.
Federico Papini - Graphic & Motion Designer. He creates visual content for the firm.
Akcan Istif - Head of Innovation & Labs. He leads the innovation initiatives within the organization.
Alessio Di Loreto - Scientific Project Manager. He manages scientific projects and collaborations.
Simone Pesce - Science & Tech Project Manager. He oversees technology projects and research initiatives.
To pitch to Scientifica, founders should visit their website at scientifica.vc. The firm prefers detailed pitch decks that clearly outline the startup's innovation, market potential, and team qualifications. While specific application forms are not mentioned, a well-structured presentation is essential.
Response times may vary, but founders are encouraged to follow up if they do not receive feedback within a reasonable timeframe. Warm introductions are beneficial but not strictly necessary.
Scientifica runs the 'Scientifica Fellowship' program, which provides innovative scientists with work contracts to enhance collaboration within its portfolio. Additionally, they operate the 'Super Sapiens Europe' accelerator program, which recently selected nine deep tech startups for its latest cohort.
In November 2025, Scientifica announced its 16th investment, focusing on deep tech startups in Italy. Recent notable investments include SPiN, which focuses on advanced networking solutions, and ExoLab Italia, which engages in space biotechnology. Additionally, OhmSpace secured a €2.5 million seed round, co-invested with CDP Venture Capital.
Scientifica continues to actively deploy capital from its €200 million fund, launched in December 2024, and is committed to supporting innovative technologies across various sectors. The firm has also established strategic partnerships with Fondazione ENEA Tech and French institutions for quantum technologies, enhancing its investment capabilities.
What are Scientifica's investment criteria?
Scientifica invests in deep tech sectors, focusing on advanced technologies such as AI, biotech, and climate tech. The firm supports startups at various stages, from Friends & Family to Series F and Growth Equity, with check sizes ranging from $50K to $500K.
How can I apply or pitch to Scientifica?
Founders can pitch their ideas through Scientifica's website at scientifica.vc. The firm encourages detailed presentations that highlight the innovation and market potential of the startup.
What makes Scientifica different from other VCs?
Scientifica combines capital with specialized expertise and advanced technological infrastructure, including its own laboratory hub in L'Aquila. This unique operational model allows for deeper collaboration and support for portfolio companies.
What is Scientifica's geographic scope?
Scientifica primarily invests in startups located in Italy and across Europe, focusing on companies that leverage the region's strong research base.
What is Scientifica's post-investment involvement like?
Scientifica provides access to its laboratory facilities, specialized expertise, and strategic partnerships to support portfolio companies in their growth and development.
What is the size of Scientifica's fund?
Scientifica manages a fund size of €200 million, which is actively deployed across various deep tech investments.
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