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SANTÉ is a healthcare investment organization founded in 2006, headquartered in Austin, Texas, with an additional office in Boston, Massachusetts. The firm focuses on investing in innovative healthcare companies, particularly in the sectors of Biotech, Medtech, and Healthtech. Currently, SANTÉ manages approximately $800 million in assets under management across five funds, with Fund V recently raising $330 million, exceeding its $300 million target.
Over the years, SANTÉ has built a strong reputation for its technology-driven approach to uncovering new investment opportunities. The firm employs a proprietary software platform known as MindRank™, which aids in identifying promising investment opportunities in publicly traded securities. This unique approach has allowed SANTÉ to maintain a portfolio of 121 companies, showcasing its commitment to advancing healthcare technologies.
Notable milestones include multiple successful exits to major acquirers in the medtech and pharma sectors, reinforcing SANTÉ's position as a key player in the healthcare investment landscape. The firm’s deep industry relationships and expertise in the healthcare domain further enhance its ability to deliver attractive returns to its investors.
SANTÉ invests primarily in early-stage healthcare companies, specifically targeting the pre-seed, seed, and seed-plus stages. The firm concentrates its efforts on sectors such as Biotech, Medtech, and Healthtech, with a geographic focus on the United States. SANTÉ seeks to partner with exceptional teams that demonstrate the potential to develop disruptive technologies aimed at improving patient health outcomes.
The organization employs its proprietary MindRank™ software to identify investment opportunities, which allows for a data-driven approach to sourcing deals. This technology enhances SANTÉ's ability to pinpoint talented entrepreneurs and innovative solutions that can significantly impact the healthcare industry. The firm looks for startups that can leverage advances in biology, medicine, and information technology to create meaningful improvements in patient care.
SANTÉ's portfolio consists of 121 innovative healthcare companies, showcasing a diverse range of solutions within the biotech and medtech sectors. Notable companies include:
Additionally, SANTÉ has achieved several notable exits, including:
This strong track record of exits to major acquirers highlights SANTÉ's deep industry relationships and its ability to identify companies with significant growth potential.
Kevin Lalande: Founding Managing Director & Chief Investment Officer. Kevin has extensive experience in healthcare investments and has led numerous successful funding rounds.
Joe Cunningham, MD: Founding Managing Director. Joe brings a medical background to the firm, enhancing its focus on healthcare innovation.
Douglas French: Founding Managing Director. Douglas has a strong track record in venture capital and healthcare investments.
James Eadie, MD: Managing Director. James specializes in medical technology investments and has a background in clinical practice.
Omar Khalil: Managing Director. Omar has significant experience in healthcare finance and investment strategies.
Dennis McWilliams: Managing Director. Dennis focuses on identifying and supporting innovative healthcare startups.
Casey Cunningham, MD: Partner & Chief Scientific Officer. Casey's medical expertise informs SANTÉ's investment decisions.
Ashley Seehusen: Venture Partner. Ashley contributes to sourcing and evaluating potential investments.
Louis Bock: Venture Partner. Louis has a background in healthcare entrepreneurship and investment.
Thomas Krummel, MD: Venture Partner. Thomas brings clinical insights to the investment process.
William Cohn, MD: Venture Partner. William has extensive experience in medical device innovation.
Jason Brandt: Chief Financial Officer & Chief Compliance Officer. Jason oversees financial operations and compliance.
Brooke Jones: Head of Capital Formation. Brooke is responsible for fundraising and investor relations.
Diane Brouillard: Head of Talent & Networks. Diane focuses on building relationships with key industry players.
Michael Hoffman: Senior Advisor. Michael provides strategic guidance to the firm.
Auriel August, MD: Principal. Auriel specializes in evaluating healthcare investments.
Michael Gutbrod: Principal. Michael focuses on sourcing new investment opportunities.
Mateo Vargas: Senior Associate. Mateo supports due diligence and portfolio management.
Alana Horowitz: Senior Associate. Alana assists in evaluating potential investments.
Stéphane Peluso: Venture Fellow. Stéphane contributes to research and analysis.
Brandon Felkins: Venture Fellow. Brandon supports the investment team in various capacities.
Jake Rogers: Head of Operations. Jake manages day-to-day operations at SANTÉ.
Ryan Hall: Associate. Ryan assists in deal sourcing and analysis.
Ryan Harty: Associate. Ryan supports portfolio management efforts.
Kyle Schroeder: Senior Analyst. Kyle conducts market research and analysis.
Chas Juliano: Controller. Chas oversees financial reporting and compliance.
Shannon Czimskey: Senior Financial Accountant. Shannon manages financial records and reporting.
Laura McMillian: Office Manager. Laura oversees administrative functions at SANTÉ.
To pitch to SANTÉ, founders should submit their proposals through the firm's website at sante.com. It is essential to include a comprehensive deck that outlines the business model, market opportunity, and team qualifications. SANTÉ prefers warm introductions but will consider direct submissions as well. Response times may vary, but founders can expect feedback within a few weeks.
In March 2026, SANTÉ announced the successful closing of Fund V, raising $330 million, which exceeded its initial target of $300 million. This fund will continue to focus on early-stage healthcare investments.
Throughout 2025, SANTÉ made several notable investments, including ABK Biomedical and beHuman, both of which are advancing innovative solutions in the healthcare sector. The firm has also seen successful exits, including Laminar, which was acquired by Johnson & Johnson, and Farapulse, which was acquired by Boston Scientific.
SANTÉ's portfolio continues to grow, with a total of 121 investments, reflecting its commitment to identifying and supporting disruptive healthcare technologies.
What are SANTÉ's investment criteria?
SANTÉ focuses on early-stage healthcare companies in the Biotech, Medtech, and Healthtech sectors. The firm seeks exceptional teams with disruptive technologies that can improve patient health outcomes.
How can I apply or pitch to SANTÉ?
Founders can pitch their ideas through the SANTÉ website at sante.com. It is advisable to include a detailed business plan and information about the founding team.
What makes SANTÉ different from other investors?
SANTÉ utilizes its proprietary MindRank™ software for investment sourcing, which provides a unique data-driven approach to identifying promising healthcare innovations. This technology, combined with deep industry relationships, enhances their investment strategy.
What is SANTÉ's geographic scope?
The firm primarily focuses on investments within the United States, targeting early-stage healthcare companies that demonstrate significant potential for growth.
What is SANTÉ's fund size and check size?
SANTÉ manages approximately $800 million in assets under management, with Fund V totaling $330 million. Check sizes typically vary based on the stage of investment but are generally aligned with early-stage funding rounds.
What is SANTÉ's post-investment involvement like?
SANTÉ actively engages with its portfolio companies, leveraging its industry relationships and expertise to support growth and development. The firm often provides operational support and strategic guidance to help companies achieve their objectives.
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