The Founder's Guide to

Immune Boost Capital

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Overview

Immune Boost Capital (IBC) is the philanthropic venture subsidiary of the Arthritis National Research Foundation (ANRF), established to invest in early-stage autoimmune diagnostics and therapeutics. Founded in October 2025, IBC operates independently while being guided by a team of experienced investors, scientists, and healthcare leaders. The fund is designed to recycle 100% of returns to support future innovation, ensuring that successful investments contribute to ongoing advancements in the field.

IBC's mission is to bridge the funding gap between academic discovery and clinical development in autoimmune diseases. The fund focuses on early-stage investments, particularly in diagnostics and therapeutics that are at or before preclinical proof-of-concept. IBC is based in Los Angeles, California, and aims to support academic spinouts and emerging biotech companies that are pursuing innovative solutions in autoimmune and inflammatory diseases.

As a philanthropic evergreen venture fund, IBC does not distribute capital returns to donors or management. Instead, all returns are reinvested into future mission-aligned investments, reinforcing its commitment to advancing research and development in the autoimmune sector.

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Frequently Asked Questions

What are Immune Boost Capital's investment criteria?

IBC focuses on early-stage investments in autoimmune and inflammatory diseases, specifically targeting diagnostics and therapeutics at or before preclinical proof-of-concept. The fund seeks to support academic spinouts and emerging biotech companies with compelling early data.

How can founders apply or pitch to Immune Boost Capital?

Founders can pitch their ideas by visiting the IBC website at immuneboostcapital.org or by emailing their proposals to info@immuneboostcapital.org. It is advisable to include detailed information about the technology, market potential, and any preliminary data.

What makes Immune Boost Capital different from traditional VCs?

IBC operates as a philanthropic venture fund, meaning that all returns from successful investments are reinvested into future innovations rather than distributed to donors or management. This mission-first approach allows IBC to focus on supporting early-stage projects that may not yet attract traditional venture capital.

What is the typical check size for investments?

IBC provides initial and co-investments ranging from $100,000 to $500,000, with potential follow-on investments to support further development of portfolio companies.

What is the geographic focus of Immune Boost Capital?

While IBC primarily focuses on U.S.-based opportunities, it does not explicitly restrict its investments to a specific geographic area. The fund is open to innovative projects that align with its mission, regardless of location.

What kind of post-investment support does Immune Boost Capital provide?

IBC offers strategic guidance to portfolio companies, helping them navigate the path from early-stage development to clinical readiness. This support is aimed at ensuring that companies can effectively advance their technologies and achieve their milestones.

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