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F-Prime Capital

F-Prime Capital is a venture capital firm based in Cambridge, Massachusetts, with additional offices in London and San Francisco. It focuses on investments in life sciences, technology, healthtech, and crypto, managing approximately $4.8 billion in assets.

Recorded stages
Friends Family, Angel, Accelerator, Pre Seed, Seed, Seed Plus, Series A, Series A Plus, Series B, Series B Plus, Series C, Series C Plus, Series D, Series E, Series F, Growth Equity, Pre Ipo, Ipo, Secondary, Bridge, Recap
Recorded regions
United States, United Kingdom, Global

Online destinations

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Overview

F-Prime Capital is a venture capital firm founded over 50 years ago, based in Cambridge, Massachusetts, with additional offices in London and San Francisco. The firm focuses on enabling companies to achieve breakthroughs in life sciences, technology, healthtech, and crypto. It manages approximately $4.8 billion in assets and has a portfolio that includes over 212 global companies. F-Prime Capital employs a stage-agnostic strategy, prioritizing early-stage investments while also supporting exceptional teams at any stage. Notable portfolio companies include Beam Therapeutics, Toast, and Devoted Health. The firm also offers a Life Sciences Summer Fellowship for MD and/or PhD students, providing a stipend for participants.

Focus

F-Prime Capital invests across a range of sectors, including life sciences (therapeutics and medtech), technology (enterprise software, fintech, and frontier tech), healthtech, and crypto. The firm is stage-agnostic, primarily focusing on early-stage investments but is also willing to support exceptional teams at any stage of their development.

Support

F-Prime Capital adds value to its portfolio companies through strategic guidance, industry expertise, and access to a broad network of resources. The firm supports its companies in navigating challenges and scaling their operations effectively.

Questions

What are F-Prime Capital's investment criteria?

F-Prime Capital focuses on early-stage investments in sectors such as healthcare, technology, biotech, fintech, and SaaS. They typically invest between $5 million and $30 million.

How can startups apply or pitch to F-Prime Capital?

Startups can submit their pitch through the contact form on F-Prime Capital's website. They encourage detailed presentations that highlight the company's vision, market potential, and team.

What makes F-Prime Capital different from other venture capital firms?

F-Prime Capital benefits from Fidelity's backing, which provides significant resources without the pressure of outside fundraising. This allows them to focus entirely on supporting entrepreneurs.

What is F-Prime Capital's geographic scope?

F-Prime Capital primarily invests in North America and Europe, with a sister fund, Eight Roads, covering investment opportunities in Asia.

What is F-Prime Capital's post-investment involvement like?

F-Prime Capital provides operational support and strategic guidance to its portfolio companies, leveraging its extensive network and resources.

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