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Breakthrough Venture Capital is an early-stage investment fund based in Wyoming, focused on high-growth startups in the Mountain West. The firm partners with companies primarily in healthcare, biotech, and digital health, with a fund size that allows for initial investments between $500,000 and $750,000. They emphasize value creation through intentional investments and support for founders navigating growth milestones.
This firm invests in Seed to Series A companies headquartered in or expanding into the Mountain West region. Breakthrough Venture Capital typically commits between $500,000 and $750,000, with additional capital reserved for follow-on investments. They look for startups with exceptional founder-market fit, early commercial traction, meaningful differentiation, scalability beyond regional markets, and alignment with their operator-driven approach.
Notable portfolio companies include Derapi, which connects distributed energy devices with management platforms; CellDrop Biosciences, a cell therapy company developing biologic medicines for pets and people; Eye to Eye Telehealth, focused on connected devices for glaucoma care; Alpyn Beauty, a skincare brand featured in major retailers; and RedDrop Dx, which manufactures a next-generation blood sampling system.
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