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The startup scene in United States
Missouri State University's efactory is located in downtown Springfield, Missouri. Its programs page lists confidential consulting, resource partners, mentorship, incubator and coworking space, and academic partnerships for prospective and current business owners and managers; the listed service scope includes a Springfield hub, southwest Missouri, and a statewide network. [93209, 93212]
About
Missouri State University's efactory is located in downtown Springfield, Missouri. Its programs page lists confidential consulting, resource partners, mentorship, incubator and coworking space, and academic partnerships for prospective and current business owners and managers; the listed service scope includes a Springfield hub, southwest Missouri, and a statewide network. [93209, 93212]
Historical examples include AgButler, which efactory reported as a Cohort 5 participant in 2021 and described as offering an agricultural labor marketplace, and MiddleCoast Solutions' HeroHub, described in 2021 as AI-assisted emergency-response software with an announced CoxHealth pilot in southwest Missouri clinics. These reports do not establish current operations or deployment, or that either company was founded in Springfield. Separately, efactory's 2025 impact report records statewide network results, not Springfield-only totals. [93222, 93223, 93214]
Startup ecosystem standing
Where Springfield ranks
| Ranking | Edition | Position | Since last edition | Trust | What it measures |
|---|---|---|---|---|---|
 Global Startup Ecosystem Index (cities) | 2025 | #397 | No prior edition | B | Ecosystem, Activity, Finance, Business Climate |
8 organizations with a profile
Who's based in Springfield
Investors 5
Investor
InvestorConnecting new angel investors with opportunities in the Northeast.
InvestorInvesting in New England's hidden gems.
The 3 most prominent of 5. Browse all investors
Accelerators 2
AcceleratorSupporting early-stage startups through mentorship and education.
AcceleratorAccelerating speakers to TEDx success.
Incubators 1
IncubatorSupporting entrepreneurs and businesses in southern Missouri.
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Your way in
Raising in Springfield
Investors based here, and the programs that take teams at your stage.
Get investor introsFinding startups in Springfield
Accelerators and incubators here see the earliest teams first.
Get startups that fitScouting in Springfield
Campuses and communities are where teams form before anyone funds them.
Start scoutingFrom public sources
What the sources say about Springfield
efactory's 2021 post identifies HeroHub, its product and reported CoxHealth pilot.
Source: Startup Companies Share Major Announcements at Demo DayThe inspected event page gives the audience, eight-session format, exact dates, no-fee condition and registration route.
Source: Early-Stage Business Boot Camp — Greene CountyIndependent 2024 Agri-Pulse coverage reports founder Kevin Johansen and an approximately 3,000-user, 42-state platform at that time.
Source: Entrepreneurs Help Revitalize Rural Revenuesefactory's 2021 post reports AgButler's product, user metrics and named agricultural partnerships.
Source: Startup Companies Share Major Announcements at Demo DayBiz 417's September 2017 feature reports the historic accelerator terms and institutional funding partners.
Source: Ready, Set, Accelerate: Inside The eFactory's Accelerator Program1908's official page identifies operator, audience, offerings and Springfield scope.
Source: 1908 Innovation & Coworking Center
Questions about Springfield
How does Springfield rank as a startup ecosystem?
Its best position is #397 in StartupBlink Index (cities) (2025).
How many startup investors are based in Springfield?
5 investors based in Springfield have a profile here, including Community Business Partnership, River Valley Investors and The Alchemy Fund. The real number is higher.
Are there accelerators or incubators in Springfield?
Yes. Springfield has 2 accelerators and 1 incubator on record, including Valley Venture Mentors and efactory.
Geographic proximity
Nearby cities to Springfield
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