InvestorBuilding secure, productive, and just communities globally.
Portland has bioscience commercialization infrastructure in South Waterfront: OBI provides lab and mentoring infrastructure for bioscience startups, and reports more than 30 companies and more than 29,000 square feet of space. [29169] OTRADI describes a pathway connecting university science to bioscience startup formation and financing. [29170] OHSU offers licensing and commercialization support to inventors. [29168]
Portland has bioscience commercialization infrastructure in South Waterfront: OBI provides lab and mentoring infrastructure for bioscience startups, and reports more than 30 companies and more than 29,000 square feet of space. [29169] OTRADI describes a pathway connecting university science to bioscience startup formation and financing. [29170] OHSU offers licensing and commercialization support to inventors. [29168]
OHSU identifies ProMedix as an OHSU-founded startup developing circulation assessment technology for sepsis detection; the company won the $200,000 Growth Stage prize at the 2024 Bend Venture Conference. [29173,29174] OHSU also reports that Siloam Vision commercialized licensed OHSU technology in a handheld OCT system for retinopathy of prematurity and received a $1.25 million Air Force contract for AI-assisted retinal imaging. [29175,29176]
The 2025 Oregon Innovation Showcase in Portland brought together OHSU, Oregon State University, the University of Oregon, Portland State University, and Business Oregon. OHSU reported more than 300 attendees from 11 states, 88 startup tables, 27 partner exhibits, and 19 sponsors. [29172]
Startup Genome reports $15 billion in ecosystem value for its Portland profile for H2 2023–2025, using exits plus startup valuations and including active unicorns; it reports $507 million in Seed and Series A tech funding for the same period and $11 billion in exits for 2021–2025. [29177,29178,29179] These figures are attributed to Startup Genome and describe its Portland profile. [29177,29178,29179]
This month
11 startup events in the next 30 days, 1 this week, 11 free. The city as a calendar, with the hosts and venues that keep it full.
Today, Saturday, Oct 31
Saturday, Nov 7
Thursday, Nov 12
Friday, Nov 13
Startup ecosystem standing
| Ranking | Edition | Position | Since last edition | Trust | What it measures |
|---|---|---|---|---|---|
| 2025 | #59 | No prior edition | B | Ecosystem, Activity, Finance, Business Climate | |
| 2026 | #77 | Down 4 | B | Innovation, Research, Activity | |
| 2026 | 21 to 30 | No prior edition | C | Ecosystem, Performance, Finance, Talent |
90 organizations with a profile
InvestorBuilding secure, productive, and just communities globally.
InvestorTailored financing solutions for businesses and commercial real estate.
InvestorInvestment firm specializing in mortgage lending and real estate.
The 3 most prominent of 56. Browse all investors
IncubatorEmpowering Black and Brown artists through art and community.
IncubatorBridging research and commercial bioscience ventures.
IncubatorEmpowering entrepreneurs through support and resources.
The 3 most prominent of 15. Browse all incubators
AcceleratorEmpowering Maine entrepreneurs through training and mentorship.
AcceleratorFostering collaboration between startups and established entities.
AcceleratorAccelerating outdoor startups in Central Oregon.
The 3 most prominent of 14. Browse all accelerators
Venture studioCatalyzing innovation and growth for brands.
Venture studioTransforming scientific discoveries into commercial ventures.
Venture studioDesigning and building the future.
The 3 most prominent of 5. Browse all venture studios
Pick what describes you
Investors based here, and the programs that take teams at your stage.
Get investor introsAccelerators and incubators here see the earliest teams first.
Get startups that fitCampuses and communities are where teams form before anyone funds them.
Start scoutingFrom public sources
Vacasa's own 2018 release provides a dated Portland headquarters and growth snapshot.
Source: Vacasa to Move Headquarters to New Heartline BuildingPortland Monthly documented Vacasa's historical local scale and fast growth.
Source: Portland-Based Vacasa Is Shaking Up the Vacation Rental GameStartup Genome reports $11 billion in exits for its Portland profile.
Source: Portland Ecosystem by the NumbersOHSU offers licensing and commercialization support to inventors.
Source: Technology TransferStartup Genome reports $507 million in early-stage tech funding for its Portland profile.
Source: Portland Ecosystem by the NumbersStartup Genome reports $15 billion under its stated Portland ecosystem-value method.
Source: Portland Ecosystem by the NumbersPortland is #59 of 1,473 in StartupBlink Index (cities) (2025). It appears in 3 published rankings; the table above lists each one.
56 investors based in Portland have a profile here, including Mercy Corps, Simple Finance and Aspen Capital. The real number is higher.
Yes. Portland has 14 accelerators, 15 incubators and 5 venture studios on record, including Maine Center for Entrepreneurs, Indigo Arts Alliance and Verify Venture Studio.
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