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The startup scene in United States

Portland has bioscience commercialization infrastructure in South Waterfront: OBI provides lab and mentoring infrastructure for bioscience startups, and reports more than 30 companies and more than 29,000 square feet of space. [29169] OTRADI describes a pathway connecting university science to bioscience startup formation and financing. [29170] OHSU offers licensing and commercialization support to inventors. [29168]

Population
652,503
Time zone
America/Los_Angeles
Fig. 1202 · St. Johns Bridge

About

Portland has bioscience commercialization infrastructure in South Waterfront: OBI provides lab and mentoring infrastructure for bioscience startups, and reports more than 30 companies and more than 29,000 square feet of space. [29169] OTRADI describes a pathway connecting university science to bioscience startup formation and financing. [29170] OHSU offers licensing and commercialization support to inventors. [29168]

OHSU identifies ProMedix as an OHSU-founded startup developing circulation assessment technology for sepsis detection; the company won the $200,000 Growth Stage prize at the 2024 Bend Venture Conference. [29173,29174] OHSU also reports that Siloam Vision commercialized licensed OHSU technology in a handheld OCT system for retinopathy of prematurity and received a $1.25 million Air Force contract for AI-assisted retinal imaging. [29175,29176]

The 2025 Oregon Innovation Showcase in Portland brought together OHSU, Oregon State University, the University of Oregon, Portland State University, and Business Oregon. OHSU reported more than 300 attendees from 11 states, 88 startup tables, 27 partner exhibits, and 19 sponsors. [29172]

Startup Genome reports $15 billion in ecosystem value for its Portland profile for H2 2023–2025, using exits plus startup valuations and including active unicorns; it reports $507 million in Seed and Series A tech funding for the same period and $11 billion in exits for 2021–2025. [29177,29178,29179] These figures are attributed to Startup Genome and describe its Portland profile. [29177,29178,29179]

This month

On in Portland this month

11 startup events in the next 30 days, 1 this week, 11 free. The city as a calendar, with the hosts and venues that keep it full.

All events in Portland

Today, Saturday, Oct 31

Hacktoberfest Hack Day Portland x Portland AI Devs

Hackathon · Varshith Chennuru · Portland State University Business Accelerator
Free

Saturday, Nov 7

Hack for Humanity: Portland, OR

The AI Collective
Free

FULL SPECTRUM Immersive Art Exhibition: Opening Night Party!

Conference · FULL SPECTRUM XR · Daydreamer Coffee & Public House
Free

Thursday, Nov 12

AI and Students: What's Actually Happening

Meetup · AI Portland
Free

Friday, Nov 13

Startup Couve Coffee

Meetup · Eliza Storey · Vancouver Innovation Center
Free
Regular hostsAI Portland · 2Eliza Storey · 2Josh Carter · 2KindsMeetups · 3Mixers · 2Conferences · 1

Startup ecosystem standing

Where Portland ranks

Rankings that list Portland
RankingEditionPositionSince last editionTrustWhat it measures
Global Startup Ecosystem Index (cities)2025#59No prior editionBEcosystem, Activity, Finance, Business Climate
Global Innovation Index: Innovation Cluster Ranking (formerly Science and Technology Clusters)2026#77Down 4BInnovation, Research, Activity
Emerging Ecosystems Ranking (GSER Top 100)202621 to 30No prior editionCEcosystem, Performance, Finance, Talent
Positions come from each publisher's edition. Open a ranking for its method and trust notes, or an edition for the full list.

90 organizations with a profile

Who's based in Portland

Investors 56

Mercy Corps logoInvestor

Building secure, productive, and just communities globally.

Simple Finance logoInvestor

Tailored financing solutions for businesses and commercial real estate.

Aspen Capital logoInvestor

Investment firm specializing in mortgage lending and real estate.

The 3 most prominent of 56. Browse all investors

Incubators 15

The 3 most prominent of 15. Browse all incubators

Accelerators 14

The 3 most prominent of 14. Browse all accelerators

Venture studios 5

Ateklo logoVenture studio

Transforming scientific discoveries into commercial ventures.

Neue Alchemy logoVenture studio

Designing and building the future.

The 3 most prominent of 5. Browse all venture studios

Pick what describes you

Your way in

From public sources

What the sources say about Portland

Questions about Portland

How does Portland rank as a startup ecosystem?

Portland is #59 of 1,473 in StartupBlink Index (cities) (2025). It appears in 3 published rankings; the table above lists each one.

How many startup investors are based in Portland?

56 investors based in Portland have a profile here, including Mercy Corps, Simple Finance and Aspen Capital. The real number is higher.

Are there accelerators or incubators in Portland?

Yes. Portland has 14 accelerators, 15 incubators and 5 venture studios on record, including Maine Center for Entrepreneurs, Indigo Arts Alliance and Verify Venture Studio.

Geographic proximity

Nearby cities to Portland

All cities in United States

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