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Founded in 2013, 645 Ventures is a venture capital firm based in New York City and San Francisco. The firm focuses on partnering with founders to build innovative technology companies, particularly in sectors such as SaaS, commerce, healthcare, and fintech. 645 Ventures has a total of 75 portfolio companies and manages approximately $550 million in assets under management (AUM), with a fund size of $160 million.
Over the years, 645 Ventures has established a reputation for its data-driven investment approach, utilizing proprietary software tools to identify and support transformative businesses. The firm has achieved notable milestones, including successful exits for companies like Iterable, Eden Health, and FiscalNote. Their office locations in major tech hubs allow them to maintain a strong presence in the startup ecosystem.
645 Ventures invests across various sectors, emphasizing themes such as Citizen Professional, SaaS for the 2nd Wave, Engineering Value Chain Revolution, and Personalized Consumer. The firm targets early-stage investments, specifically Seed, Series A, and Series B rounds, with check sizes ranging from $1 million to $20 million. Their geographic focus is primarily North America, but they also consider global opportunities.
The firm is particularly interested in software applications that enhance productivity, cloud-based solutions for previously un-penetrated business areas, and consumer companies that leverage personalized data to improve customer experiences. 645 Ventures seeks founders who demonstrate a strong vision and the ability to execute their ideas effectively, often looking for innovative approaches to traditional markets.
645 Ventures has a diverse portfolio of 75 companies, showcasing its commitment to various sectors. Notable portfolio companies include:
These companies reflect 645 Ventures' focus on technology-driven solutions that address modern consumer and business needs.
Aaron Holiday: Co-Founder and Managing Partner. Aaron has extensive experience in venture capital and has led numerous successful investments in technology companies.
Nnamdi Okike: Co-Founder and Managing Partner. Nnamdi is a Harvard Business School alum and has been featured in Forbes for his contributions to the venture capital space.
Blair Flicker: Senior Advisor with a background in technology investments and strategic consulting.
Vardan Gattani: Investment Partner with expertise in SaaS and fintech sectors.
Jon Smith: Principal focused on early-stage investments and portfolio management.
Parul Singh: Investment Partner with a strong background in technology and operational support.
Mendy Yang: Vice President involved in deal sourcing and due diligence.
William Hess: Vice President with experience in scaling startups and operational strategy.
Yasmeena Faycurry: Senior Associate focused on market research and analysis.
Pete Keenan: Managing Director and Head of Finance, overseeing financial operations.
Chonlathit Jittachalothorn: Controller managing financial reporting and compliance.
Lexi Quirk: Head of Product, responsible for product strategy and development.
Randi Jakubowitz: Head of Talent, focusing on recruitment and team development.
Kelly Hardeman: Head of Investor Relations, managing relationships with limited partners.
Meredith Tibbals: Vice President involved in investment strategy and portfolio management.
Stephen Lang: Designer contributing to branding and marketing efforts.
Christina Siadat: Office Manager and Executive Assistant supporting daily operations.
Britt Binler: Senior Software Engineer II focused on technology development.
Eric Parshall: Senior Software Engineer II contributing to software solutions.
Natasha Bradley: Executive Assistant and Office Manager supporting administrative functions.
To pitch to 645 Ventures, founders should visit their website at 645ventures.com for guidelines. They prefer pitches to be submitted via email to ideas@645ventures.com. Founders should include a comprehensive deck that outlines their business model, market analysis, and growth strategy. Response times can vary, but founders should expect to hear back within a few weeks.
Warm introductions are beneficial but not mandatory. The firm encourages direct outreach from founders who believe their business aligns with their investment focus.
On October 16, 2025, 645 Ventures made its latest investment, continuing its trend of active deployment in the venture capital space. In the past 12 months, the firm has completed 8 investments, showcasing its commitment to supporting innovative startups.
Recent notable deals include a $120 million Series A investment in Shop Circle, co-led with 3VC, and a $12 million Series A investment in Clerq. The firm also led a $7 million seed round for Meridian and a $20 million Series A for Sequence, partnering with Andreessen Horowitz.
Additionally, 645 Ventures participated in a $25 million Series B for Uptiq and extended its investment in Shop Circle's Series B to $100 million, demonstrating its active role in supporting portfolio companies through various funding stages.
What are 645 Ventures' investment criteria?
645 Ventures invests in early-stage companies across sectors such as SaaS, commerce, healthcare, and fintech. They focus on themes like cloud-based software adoption and personalized consumer data.
How can founders apply or pitch to 645 Ventures?
Founders can pitch their ideas by visiting the 645 Ventures website at 645ventures.com or by emailing their pitch to ideas@645ventures.com. They recommend including a clear business model and market analysis in the pitch deck.
What makes 645 Ventures different from other firms?
645 Ventures utilizes a data-driven approach, leveraging proprietary software tools to enhance their investment decisions. This methodology allows them to identify high-potential startups effectively.
What is the geographic scope of 645 Ventures?
The firm primarily focuses on North America but is open to global investment opportunities, particularly in technology sectors.
What is 645 Ventures' post-investment involvement like?
645 Ventures provides strategic guidance and access to a network of resources to help portfolio companies accelerate growth. They emphasize collaboration with founders to drive innovation.
What is the typical check size for investments?
645 Ventures typically invests between $1 million and $20 million in their portfolio companies, depending on the stage and potential of the business.
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