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Founded in 2021, Scientifica is an Italian venture capital organization dedicated to fostering scientific innovation and responsible investment practices within the European technology landscape. With a fund size of €200 million, Scientifica is based in Italy and operates a unique model that combines capital with specialized expertise and advanced technological infrastructure. This includes its own laboratory hub located in L'Aquila, which provides portfolio companies with access to essential resources for research and development. The firm is committed to integrity, transparency, and respect, aiming to support startups that are at the forefront of technological advancement.
Scientifica has quickly established itself as a key player in the venture capital space, focusing on deep tech sectors such as Artificial Intelligence, BioTech, HealthTech, ClimateTech, and Advanced Materials. The firm operates specialized investment vehicles, including Scientifica Fund 1 and Quantum Italia, to cater to the diverse needs of startups at various stages of development, from initial ideas to scale-up phases. With a portfolio of 16 companies, Scientifica is well-positioned to leverage Italy's strong research base and patent portfolio to drive innovation and growth in the technology sector.
Scientifica's investment focus is centered on deep tech sectors, emphasizing advanced technologies that have the potential to transform industries and improve lives. The firm invests in areas such as Artificial Intelligence, Quantum Technologies, BioTech, HealthTech, ClimateTech, and Advanced Materials. Scientifica supports startups across a wide range of stages, from Friends & Family and Angel rounds to Series A through Series F and Growth Equity. The typical check size ranges from €50,000 to €500,000, allowing for flexibility in funding depending on the specific needs of each startup.
In addition to financial support, Scientifica provides its portfolio companies with access to its laboratory facilities and specialized expertise, fostering an environment conducive to innovation and collaboration. The firm actively seeks out founders and companies that demonstrate a strong commitment to scientific advancement and responsible practices. By leveraging its extensive network and resources, Scientifica aims to empower startups to achieve their full potential and make a significant impact in their respective fields.
Scientifica's portfolio consists of 16 innovative companies across various deep tech sectors. Notable investments include Small Pixels, Principled Intelligence, PREM AI, Loto Biotech, and Platform LayerLogic. These companies are at the forefront of technological advancements in areas such as AI, biotech, and climate solutions. For instance, Small Pixels focuses on developing cutting-edge imaging technologies, while Loto Biotech is dedicated to advancing biotechnological solutions for healthcare.
Other significant portfolio companies include QSENSATO, PlantBit, Blemishhh, Aviogel, CyLock, Fluid Wire Robotics, Recornea, Sense4Med, SPiN, OhmSpace, QuantaBrain, GenomeUp, Relicta, Green Independence, Libera Biotech, Vbite, Brief, and ExoLab Italia. Scientifica's diverse portfolio reflects its commitment to investing in companies that are not only innovative but also have the potential to create a positive impact on society and the environment.
Riccardo D'Alessandri - Managing Partner, with extensive experience in venture capital and a focus on deep tech investments.
Patrick Leoni Sceti - General Partner, specializing in supporting innovative startups within the technology sector.
To pitch Scientifica, founders should visit their official website at scientifica.vc. The firm welcomes pitches that clearly outline the business model, market opportunity, and alignment with their investment focus on deep tech sectors. While warm introductions are beneficial, cold applications are also accepted.
Scientifica operates the 'Scientifica Fellowship' program, which provides innovative scientists with work contracts to foster collaboration and innovation within its portfolio. This program is designed to support the development of groundbreaking technologies and enhance the capabilities of portfolio companies. Additionally, Scientifica runs the 'Super Sapiens Europe' accelerator program, which selects deep tech startups for mentorship and funding opportunities.
Scientifica has been actively expanding its portfolio, with notable recent investments including Small Pixels and Loto Biotech. The firm is currently deploying capital from its €200 million fund, Scientifica Fund 1, which was launched in December 2024. Additionally, Scientifica has established a strategic operational hub in Silicon Valley to enhance its engagement with the global startup ecosystem.
Scientifica invests across a wide range of stages, including Friends & Family, Angel, Accelerator/Incubator, Pre-seed, Seed, Seed+ (Extension), Series A, Series A+ (Extension), Series B, Series B+ (Extension), Series C, Series C+ (Extension), Series D, Series E, Series F, and Growth Equity.
Founders interested in pitching to Scientifica can submit their proposals through their official website at scientifica.vc. It is advisable to provide a clear overview of the business model, market opportunity, and how the startup aligns with Scientifica's investment focus on deep tech sectors.
Scientifica primarily focuses on deep tech sectors, including Artificial Intelligence, BioTech, HealthTech, ClimateTech, Energy, Frontier Technologies, Robotics, Industrial Tech, Commerce, and FinTech. The firm seeks to invest in innovative technologies that have the potential to drive significant advancements in these areas.
The typical check size for investments made by Scientifica ranges from €50,000 to €500,000, allowing for flexibility based on the specific needs of the startup.
Scientifica primarily invests in startups located in Europe, with a strong emphasis on the Italian technology landscape. The firm aims to support innovative companies that are contributing to the advancement of technology within the region.
Scientifica adds value to its portfolio companies through access to its laboratory facilities, specialized expertise, and strategic partnerships. The organization also runs the 'Scientifica Fellowship' program, which provides innovative scientists with work contracts to foster collaboration and innovation within its portfolio.
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